The effect of coronavirus infection (SARS-CoV-2, MERS-CoV, and SARS-CoV) during pregnancy and the possibility of vertical maternal–fetal transmission: a systematic review and meta-analysis

Coronavirus infection in pregnant women makes clinical management more difficult by prolonging and complicating the illness and compromises the treatment. Researchers are still in question regarding the transmission of the novel and previous coronavirus infection from a pregnant woman to her fetus, a process termed vertical transmission. There are few published cases of coronavirus disease occurring during pregnancy and due to the possibility of mother–fetal vertical transmission, there is a concern that the fetuses may be at risk of congenital COVID-19 and other CoV outbreaks. Due to the alarming spread of CoV outbreaks throughout the world, a comprehensive understanding of the transmission of the virus from mother to fetus in utero like other emerging viral infections as Zika virus and Ebola virus, that can threaten the health and survival of an infected mother and fetus is essential for effective management of the infection and treatment. Therefore, this systematic review and meta-analysis was aimed to assess the effect of coronavirus infection (SARS-CoV-2, MERS-CoV, and SARS-CoV) during pregnancy and its possibility of vertical maternal–fetal transmission.

The effect of coronavirus infection (SARS-CoV-2, MERS-CoV, and SARS-CoV) during pregnancy and the possibility of vertical maternal–fetal transmission: a systematic review and meta-analysis
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