Chest CT manifestations of COVID-19 pneumonia have not been well known. Recent studies showed that typical CT findings included bilateral pulmonary parenchymal ground glass and consolidative pulmonary opacities, with a peripheral lung distribution. However, the CT features of COVID- 19 are very diverse, and it is difficult to differentiate it from other kinds of viral pneumonia. Recently, Bai et al compared the chest CT features of COVID-19 pneumonia and non-COVID-19 viral pneumonia, and found that COVID-19 pneumonia was more likely to have a peripheral distribution and ground-glass opacity. However, there are several kinds of respiratory tract viruses that may lead to viral pneumonia, and the CT features of the different kinds of viral pneumonia may be different. Influenza pneumonia is among the most common viral pneumonia, and now it is just during the “flu season”; therefore, it is essential to differentiate COVID-19 pneumonia from influenza. Herein, we described and summarized the chest CT findings of 122 patients with COVID-19 pneumonia and 48 patients with influenza, and tried to explore the radiological differentiation between the two groups.