Use of PPIs Linked to Contracting COVID-19

The study, of more than 86,000 people in the United States, found that those who reported using PPIs twice a day were nearly four times as likely to test positive for the SARS-CoV-2 virus as people who did not use the medications. The risk was elevated, though less dramatically, for people who used PPIs once daily. In contrast, use of histamine-2 receptor antagonists did not appear to increase the risk for a positive test, the study found.

Use of PPIs Linked to Contracting COVID-19
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