Saliva is more sensitive for SARS-CoV-2 detection in COVID-19 patients than nasopharyngeal swabs

Efforts to control SARS-CoV-2, the novel coronavirus causing COVID-19 pandemic, depend on accurate and rapid diagnostic testing. These tests must be ( 1) sensitive to mild and asymptomatic infections to promote effective self isolation and reduce transmission within high risk groups1
; (2) consistent to reliably monitor disease progression and aid clinical decisions2; and ( 3) scalable to inform local and national public health policies, such as when social distancing measures can be safely relaxed. However, current SARS-CoV-2 testing strategies often fail to meet these criteria, in part because of their reliance on nasopharyngeal swabs as the widely recommended sample type for real-time RT-PCR.

Saliva is more sensitive for SARS-CoV-2 detection in COVID-19 patients than nasopharyngeal swabs
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